The Emperor: He serves as a close adviser and parental guardian to the young emperor. He acts not unlike a warm father towards him, using him to push his own self-serving policies. However, despite using him like a puppet he is seen at some times giving him real information and agreeing with him. For example, the time the Emperor asked about Esdeath's desire to fall in love and agreeing that it's hard to find the man she wants.
Esdeath: An ally, though the relationship between the two is strictly business oriented. Also according to Esdeath herself, the Prime Minister is safe in his position due to her aid. He often asks political favors from her in return allowing her to do what she wants. In the end, though, they are merely using each other.
Iokal: His cousin who was siphoning off of his power. Nothing is known about their relationship, but Honest wasn't happy when his cousin was killed.
Syura: His son who clearly respects him but on the other hand wishes to surpass his father. In return, while Honest shown to have great expectation for his son and call his harsh treatment being a tough love. However, when the news of Syura death reached Honest ears his remorse lasted for a moment then Honest dismissed his own son as a failure and stated that he can make another son from scrap.
Budo: The Prime Minister and the Grand General have a mutual dislike relationship. Budo is well aware of the minister's hand in causing the Empire to rot with corruption and made his intention clear to kill Honest and cleanse the Empire after dealing with the revolution. However, while Honest, due to his alliance with Esdeath, isn't that much worried about Budo's threats, he knows that if there was any evidence found against him he would be done for as shown when he learned of the document that proved Syura being behind the releasing the Danger Beasts that threatened the Capital and the whole Empire.